Apoptose, interleukine et shigellose

Do yeast apoptose?

A muscular path to quiescence uscle stem cells called satellite cells can pull back from the brink, according to Zammit et al. (page 347). When activated by muscle damage, the cells divide and start uniformly down a differentiation path. Only at the last minute do some of the cells split off to revert to a quiescent, stem cell phenotype. Satellite cells sit quietly underneath the basal lamina o...

[Interleukine-3: a multifunctional cytokine].

Normal hematopoiesis is regulated in part by a variety of growth factors (HGF) acting at different stages of cellular maturation. Among the HGF acting on early progenitors, Interleukin-3 (IL-3) is one of the first well characterized. This cytokine exhibits various biological activities including proliferative effects on hematopoietic stem cells as well as regulatory properties on mature element...

Myokardiale Apoptose und zelluläre Infiltration beim Plötzlichen Kindstod

Absolute quantification of murine interleukine-4, interleukine- 10 and interferon-γ gene transcripts using Real Time PCR

The study of cytokines gene expression is quite important in various conditions of health and disease for the evaluation of clinical responses to new vaccination approaches. An absolute quantification is based on a calibration curve and production of standard controls to achieve more reliable results than in relative system. In this study we attempted to construct standard controls to evaluate ...

Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress.

Initiation of DNA replication at origins more than once per cell cycle results in rereplication and has been implicated in cancer. Here we use Drosophila to examine the checkpoint responses to rereplication in a developmental context. We find that increased Double-parked (Dup), the Drosophila ortholog of Cdt1, results in rereplication and DNA damage. In most cells, this rereplication triggers c...